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Live Webinar on Issues in Calibrations and Accuracy in Method Validation

26468 E Walker Dr, Aurora, Colorado 80016-6104
26468 E Walker Dr, Aurora, Colorado 80016-6104 Aurora, CO 80016  
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Start:   Wednesday, February 20, 2019  1:00 PM
End:   Wednesday, February 20, 2019  2:00 PM

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Event Features: Health / Wellness

Neighborhood: Avenue of the Arts


OVERVIEW One of the most important concepts and criteria of Good Laboratory Practices is accuracy, how well does a methodology stand in terms of quantifying when compared to an expected value? There are various approaches in calibration and in the use of standards for comparisons. This webinar will cover validation of calibrations and the strengths, weaknesses, and appropriateness of the different types of standards.
Accuracy is one of the most fundamental assessments in regulated analyses and calibration is the means to determine it. The quality, and therefore the acceptability, of accuracy is a large part of an auditor’s review of a methodology.
• How accuracy is determined in analytical method development and validation
• What are the various types of standards and what are their strengths and weaknesses
• Analytical method validation and the importance of traceability
• Calibration curves – what are the important criteria?
• Linearity versus nonlinearity, slope, intercept and what they mean
• Matrix effects and how to deal with them
• Using calibration data to monitor performance
• Comparison by using standards – the types of standards
• Traceability and documentation in analytical method development and validation
• Calibration curves – checks for linearity, when non-linearity happens
• Spikes, surrogates, and standard addition
• Monitoring calibrations – slope and intercept
• Lab Chemists
• Lab Managers
• Lab Technicians
• Lab Analysts
• Industries into Compliance Methodology (Biotech, Pharma)
• Companies into Environmental Compliance (EPA)

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